Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 14/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818544 | 1.00 | CBLB (0.44) | CBLBCNR2TSHR | |
| SCHEMBL30152768 | 1.00 | CBLB (0.44) | CBLBCNR2TSHR | |
| SCHEMBL24818540 | 1.00 | CBLB (0.44) | CBLBCNR2TSHR | |
| SCHEMBL30152576 | 0.93 | CBLB (0.42) | CBLBCNR2 | |
| SCHEMBL24818660 | 0.93 | CBLB (0.42) | CBLBCNR2 | |
| SCHEMBL24820284 | 0.85 | CBLB (0.41) | CBLB | |
| SCHEMBL30153026 | 0.85 | CBLB (0.41) | CBLB | |
| SCHEMBL24818788 | 0.84 | CBLB (0.44) | CBLBCNR2 | |
| SCHEMBL24819900 | 0.84 | CBLB (0.44) | CBLBCNR2 | |
| SCHEMBL29189888 | 0.84 | CBLB (0.44) | CBLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |