Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 5/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792033 | 1.00 | HPGD (0.33) | HPGDIDO1CETPCYP11B2MAP3K5 | |
| SCHEMBL24820121 | 1.00 | HPGD (0.33) | HPGDIDO1CETPCYP11B2MAP3K5 | |
| SCHEMBL30792046 | 0.94 | MAP3K5 (0.34) | HPGDIDO1CYP11B2MAP3K5CBLB | |
| SCHEMBL24820582 | 0.94 | MAP3K5 (0.34) | HPGDIDO1CYP11B2MAP3K5CBLB | |
| SCHEMBL30152957 | 0.94 | MAP3K5 (0.34) | HPGDIDO1CYP11B2MAP3K5CBLB | |
| SCHEMBL24821974 | 0.93 | SMN1; SMN2 (0.34) | IDO1CYP11B2MAP3K5TP53CBLB | |
| SCHEMBL30792080 | 0.93 | SMN1; SMN2 (0.34) | IDO1CYP11B2MAP3K5TP53CBLB | |
| SCHEMBL30153164 | 0.93 | SMN1; SMN2 (0.34) | IDO1CYP11B2MAP3K5TP53CBLB | |
| SCHEMBL30153078 | 0.92 | HPGD (0.33) | HPGDCETPMAP3K5TP53CBLB | |
| SCHEMBL24821927 | 0.92 | CBLB (0.36) | IDO1CETPCYP11B2MAP3K5CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |