Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820582 | 1.00 | MAP3K5 (0.34) | MAP3K5IDO1CYP11B2GRM2KCNH2 | |
| SCHEMBL30152957 | 1.00 | MAP3K5 (0.34) | MAP3K5IDO1CYP11B2GRM2KCNH2 | |
| SCHEMBL30792033 | 0.94 | HPGD (0.33) | MAP3K5IDO1CYP11B2CBLBCYP11B1 | |
| SCHEMBL30152670 | 0.94 | HPGD (0.33) | MAP3K5IDO1CYP11B2CBLBCYP11B1 | |
| SCHEMBL24820121 | 0.94 | HPGD (0.33) | MAP3K5IDO1CYP11B2CBLBCYP11B1 | |
| SCHEMBL24820138 | 0.93 | MAP3K5 (0.34) | MAP3K5GRM2KCNH2CBLBALDH1A1 | |
| SCHEMBL24821974 | 0.93 | SMN1; SMN2 (0.34) | MAP3K5IDO1CYP11B2CBLBCYP11B1 | |
| SCHEMBL30153076 | 0.93 | MAP3K5 (0.34) | MAP3K5GRM2KCNH2CBLBALDH1A1 | |
| SCHEMBL30792080 | 0.93 | SMN1; SMN2 (0.34) | MAP3K5IDO1CYP11B2CBLBCYP11B1 | |
| SCHEMBL30792001 | 0.93 | MAP3K5 (0.34) | MAP3K5GRM2KCNH2CBLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |