Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 14/20 | 0.40 |
| ▸ | CBLC | Q9ULV8 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 3/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818901 | 1.00 | CBLB (0.40) | CBLBCBLCFAAHMGLLWDR5 | |
| SCHEMBL30152939 | 0.93 | CBLB (0.42) | CBLBCBLCFAAHMGLL | |
| SCHEMBL30152907 | 0.88 | CBLB (0.41) | CBLBWDR5 | |
| SCHEMBL24820707 | 0.88 | CBLB (0.41) | CBLBWDR5 | |
| SCHEMBL30152712 | 0.88 | CBLB (0.39) | CBLBCBLCWDR5 | |
| SCHEMBL24820592 | 0.88 | CBLB (0.39) | CBLBCBLCWDR5 | |
| SCHEMBL24818844 | 0.87 | CBLB (0.43) | CBLBCBLCFAAHMGLL | |
| SCHEMBL30152839 | 0.87 | CBLB (0.43) | CBLBCBLCFAAHMGLL | |
| SCHEMBL30152871 | 0.83 | CBLB (0.39) | CBLBFAAHMGLL | |
| SCHEMBL24819918 | 0.80 | CBLB (0.41) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |