Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 13/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152907 | 1.00 | CBLB (0.41) | CBLBKDM4ELMNAMAPTHPGD | |
| SCHEMBL24820513 | 0.89 | CBLB (0.37) | CBLBLMNACHRM3WDR5 | |
| SCHEMBL30152659 | 0.89 | CBLB (0.37) | CBLBLMNACHRM3WDR5 | |
| SCHEMBL30152965 | 0.88 | CBLB (0.40) | CBLBWDR5 | |
| SCHEMBL24818901 | 0.88 | CBLB (0.40) | CBLBWDR5 | |
| SCHEMBL30152712 | 0.88 | CBLB (0.39) | CBLBWDR5 | |
| SCHEMBL24820592 | 0.88 | CBLB (0.39) | CBLBWDR5 | |
| SCHEMBL30152939 | 0.82 | CBLB (0.42) | CBLB | |
| SCHEMBL29190056 | 0.79 | CBLB (0.37) | CBLB | |
| SCHEMBL30153246 | 0.79 | CBLB (0.37) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |