Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 8/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | ROS1 | P08922 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818719 | 1.00 | CBLB (0.45) | CBLBMAP3K5ROS1PDE2A | |
| SCHEMBL24820612 | 0.89 | CBLB (0.37) | CBLBROS1PDE2A | |
| SCHEMBL30152942 | 0.87 | CBLB (0.37) | CBLB | |
| SCHEMBL24821871 | 0.87 | CBLB (0.37) | CBLB | |
| SCHEMBL24820618 | 0.83 | CBLB (0.45) | CBLBROS1PDE2A | |
| SCHEMBL30152850 | 0.83 | CBLB (0.45) | CBLBROS1PDE2A | |
| SCHEMBL24819939 | 0.83 | CBLB (0.45) | CBLBROS1PDE2A | |
| SCHEMBL30152752 | 0.83 | CBLB (0.40) | CBLB | |
| SCHEMBL30792068 | 0.80 | CBLB (0.40) | CBLBPDE2A | |
| SCHEMBL29189952 | 0.79 | CBLB (0.35) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |