SCHEMBL24821871

SCHEMBL24821871

CCNc1cc(-c2c(-c3nncn3C)cnn2C)cc(-c2nc3ccc(Br)c(C(F)(F)F)c3[nH]2)n1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152942 1.00 CBLB (0.37) CBLB
SCHEMBL24820612 0.93 CBLB (0.37) CBLB
SCHEMBL30153008 0.87 CBLB (0.45) CBLB
SCHEMBL24818719 0.87 CBLB (0.45) CBLB
SCHEMBL30152752 0.77 CBLB (0.40) CBLB
SCHEMBL24821872 0.75 CBLB (0.42) CBLB
SCHEMBL24820326 0.74 CBLB (0.40) CBLB
SCHEMBL30153116 0.74 CBLB (0.40) CBLB
SCHEMBL24819939 0.74 CBLB (0.45) CBLB
SCHEMBL24820618 0.74 CBLB (0.45) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117858865-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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