Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 7/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.51 |
| ▸ | AHCY | P23526 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211035 | 0.83 | ADORA3 (0.55) | PRKACAROCK2HSP90B1AHCY | |
| SCHEMBL29378113 | 0.78 | ADORA2A (0.70) | HSP90B1 | |
| SCHEMBL3021887 | 0.78 | ENTPD2 (0.47) | PRKACAAHCY | |
| SCHEMBL3021880 | 0.78 | ENTPD2 (0.47) | PRKACAAHCY | |
| SCHEMBL3019416 | 0.77 | ENTPD2 (0.62) | PRKACA | |
| SCHEMBL3019419 | 0.77 | ENTPD2 (0.62) | PRKACA | |
| SCHEMBL3017491 | 0.73 | ENTPD2 (0.37) | PRKACAROCK2HSP90B1AHCY | |
| SCHEMBL32660834 | 0.71 | PRKACA (1.00) | PRKACAROCK2HSP90B1AHCY | |
| SCHEMBL10001410 | 0.69 | PRKACA (0.83) | PRKACAROCK2HSP90B1AHCY | |
| SCHEMBL3027404 | 0.69 | PRKACA (0.35) | PRKACAROCK2HSP90B1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019834-B1 | ECTONUCLEOTIDASE INHIBITORS | UNIV BONN (DE) | 2014-07-09 | — | — | EP | disclosed |
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204182-A1 | ECTONUCLEOTIDASE INHIBITORS | NT5E, NT5C2, ENTPD1 | PRKACA 1691/4885ROCK2 4468/4885HSP90B1 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.