Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 7/20 | 0.46 |
| ▸ | ADH1C | P00326 | 4/20 | 0.46 |
| ▸ | PHGDH | O43175 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7365290 | 0.97 | ADH1A (0.48) | ADH1AADH1CPHGDHFAAHMGLL | |
| Hydrochloric Acid SCHEMBL313575 | 0.97 | ADH1A (0.48) | ADH1AADH1CPHGDHFAAHMGLL | |
| Bromide SCHEMBL20815433 | 0.97 | ADH1A (0.48) | ADH1AADH1CPHGDHFAAHMGLL | |
| Hydrochloric Acid SCHEMBL312891 | 0.97 | ADH1A (0.48) | ADH1AADH1CPHGDHFAAHMGLL | |
| Bromide SCHEMBL28395534 | 0.97 | ADH1A (0.48) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL13356252 | 0.94 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL1674941 | 0.94 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL20733112 | 0.94 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| Hydrochloric Acid SCHEMBL313812 | 0.94 | — | — | |
| SCHEMBL283931 | 0.94 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022270282-A1 | SOLDER PASTE AND METHOD FOR PRODUCING ELECTRONIC DEVICE | 千住金属工業株式会社 | 2022-12-29 | — | — | WO | disclosed |