Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL950247 | 0.81 | — | — | |
| SCHEMBL11955052 | 0.79 | TSHR (0.46) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| Dimethylketone Cyanohydrin SCHEMBL28093947 | 0.79 | TSHR (0.46) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL1269985 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL14002143 | 0.77 | TSHR (0.43) | ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL12933281 | 0.77 | TSHR (0.43) | ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL13858659 | 0.75 | TSHR (0.42) | ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL15880576 | 0.75 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2945318 | 0.74 | ALDH1A1 (0.64) | ALDH1A1TDP1 | |
| SCHEMBL3040312 | 0.74 | ALDH1A1 (0.64) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392432-A2 | POSITIVE NMDA-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028278-A2 | POSITIVE NMDA-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |