Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.55 |
| ▸ | CTSV | O60911 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130919 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL29365383 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL16237897 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL26993708 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL170077 | 0.99 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL29355024 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL17739377 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL20604049 | 0.85 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL12891618 | 0.84 | CYP2D6 (0.68) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL17400300 | 0.84 | CYP2D6 (0.68) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730197-B1 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | HAPTOGEN LTD (GB) | 2012-03-07 | — | — | EP | claimed |