Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157800 | 0.94 | P2RX7 (0.51) | P2RX7CYP2D6CYP2C9CYP2C19NPC1 | |
| SCHEMBL30158011 | 0.90 | P2RX7 (0.50) | P2RX7CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30158093 | 0.89 | P2RX7 (0.53) | P2RX7CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30158742 | 0.88 | P2RX7 (0.59) | P2RX7ALDH1A1 | |
| SCHEMBL31551578 | 0.88 | P2RX7 (0.45) | P2RX7CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30158069 | 0.88 | P2RX7 (0.54) | P2RX7CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30862582 | 0.88 | P2RX7 (0.54) | P2RX7CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30158053 | 0.87 | P2RX7 (0.54) | P2RX7CYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30157509 | 0.86 | P2RX7 (0.61) | P2RX7ALDH1A1 | |
| SCHEMBL30157332 | 0.85 | P2RX7 (0.53) | P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |