Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157928 | 0.90 | HDAC1 (0.48) | GAAP2RX7HDAC1HDAC2KMT2A | |
| SCHEMBL30157660 | 0.83 | KMT2A (0.49) | GAAP2RX7ALDH1A1RAB9ACYP2D6 | |
| SCHEMBL30157819 | 0.82 | SMN1; SMN2 (0.51) | GAAALDH1A1RAB9ACYP2D6CYP2C19 | |
| SCHEMBL30157483 | 0.80 | GAA (0.61) | GAAP2RX7ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL30157722 | 0.80 | GAA (0.63) | GAAP2RX7ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL30158715 | 0.78 | GAA (0.59) | GAAP2RX7ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL30157600 | 0.78 | KMT2A (0.51) | GAAALDH1A1CYP2C19CYP2C9MEN1 | |
| SCHEMBL30158670 | 0.78 | PTGER2 (0.49) | P2RX7ALDH1A1NPC1RAB9AHDAC1 | |
| SCHEMBL30157628 | 0.78 | EPHX2 (0.44) | P2RX7NPC1RAB9AHDAC1HDAC2 | |
| SCHEMBL31706616 | 0.77 | CYP2D6 (0.58) | GAAP2RX7ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |