Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157928 | 0.86 | HDAC1 (0.48) | KMT2AHDAC1HDAC2P2RX7GAA | |
| SCHEMBL30157915 | 0.83 | GAA (0.60) | KMT2AHDAC1HDAC2P2RX7RAB9A | |
| SCHEMBL30157636 | 0.82 | P2RX7 (0.56) | KMT2AHDAC1HDAC2P2RX7POLB | |
| SCHEMBL30157819 | 0.82 | SMN1; SMN2 (0.51) | KMT2AHDAC1HDAC2POLBRAB9A | |
| SCHEMBL30157600 | 0.81 | KMT2A (0.51) | KMT2APOLBTSHRTP53GAA | |
| SCHEMBL30158670 | 0.80 | PTGER2 (0.49) | KMT2AHDAC1HDAC2P2RX7POLB | |
| SCHEMBL30157628 | 0.80 | EPHX2 (0.44) | KMT2AHDAC1HDAC2P2RX7POLB | |
| SCHEMBL30157530 | 0.80 | ALDH1A1 (0.51) | KMT2AHDAC1HDAC2SMN1; SMN2TSHR | |
| SCHEMBL30157582 | 0.79 | KMT2A (0.65) | KMT2AHDAC1HDAC2SMN1; SMN2LMNA | |
| SCHEMBL30157321 | 0.78 | KMT2A (0.53) | KMT2APOLBTSHRALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |