Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.72 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157577 | 0.96 | NPSR1 (0.70) | NPSR1ALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL30158025 | 0.94 | NPSR1 (0.69) | NPSR1ALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL30157629 | 0.94 | NPSR1 (0.69) | NPSR1ALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL30157749 | 0.94 | POLB (0.80) | NPSR1ALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL30157283 | 0.88 | NPSR1 (0.72) | NPSR1ALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL19419916 | 0.86 | TSHR (0.70) | NPSR1ALDH1A1APOBEC3AAPOBEC3GPOLB | |
| SCHEMBL30158807 | 0.84 | GAA (0.74) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| SCHEMBL12838810 | 0.84 | TSHR (0.73) | ALDH1A1APOBEC3AAPOBEC3GPOLBMEN1 | |
| SCHEMBL30157624 | 0.83 | SMN1; SMN2 (0.73) | NPSR1ALDH1A1HPGDAPOBEC3AAPOBEC3G | |
| SCHEMBL30157604 | 0.81 | GAA (0.68) | ALDH1A1POLBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |