Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158807 | 0.94 | GAA (0.74) | GAATDP1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL30157472 | 0.89 | ALDH1A1 (0.68) | GAASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL30157451 | 0.88 | GAA (0.67) | GAATDP1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL30157652 | 0.88 | POLB (0.71) | GAATDP1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL30158025 | 0.88 | NPSR1 (0.69) | GAATDP1ALDH1A1TSHRPOLB | |
| SCHEMBL30157577 | 0.87 | NPSR1 (0.70) | GAASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL30157964 | 0.86 | SMN1; SMN2 (0.70) | GAATDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30157502 | 0.85 | P2RX7 (0.70) | GAATDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30158578 | 0.85 | ALDH1A1 (0.60) | GAATDP1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30157592 | 0.84 | GAA (0.64) | GAATDP1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |