Sugi Predict

Sugi Predict / Compounds / SCHEMBL3015906

SCHEMBL3015906

SCHEMBL3015906

COCc1ccc(O)c(C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 9/20 0.63
▸ ESR2 Q92731 7/20 0.63
▸ TP53 P04637 2/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ AR P10275 3/20 0.44
▸ PDE10A Q9Y233 1/20 0.43
▸ THRA P10827 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ DBH P09172 1/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ LMNA P02545 1/20 0.40
▸ HSD17B1 P14061 1/20 0.40
▸ HSD17B2 P37059 1/20 0.40
▸ TSHR P16473 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ TAAR1 Q96RJ0 1/20 0.39
▸ TRPA1 O75762 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ PRKCG P05129 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4677534 0.83 TSHR (0.43) ESR1ESR2TP53TDP1LMNA
SCHEMBL3807966 0.83 TRPA1 (0.58) ESR1TP53TDP1ARLMNA
SCHEMBL16245050 0.81 CNR1 (0.55) TP53TDP1PTPN1LMNAHSD17B1
SCHEMBL8750643 0.80 NPC1 (0.42) ESR1ESR2TP53TDP1LMNA
SCHEMBL8914905 0.80 ESR1 (0.59) ESR1ESR2TP53TDP1AR
SCHEMBL25446709 0.79 PRKCE (0.47) TP53TDP1PTPN1LMNAHSD17B1
SCHEMBL20897164 0.78 PDK2 (0.42) ESR1ESR2TP53LMNA
SCHEMBL1924746 0.78 ESR1 (0.74) ESR1ESR2TP53TDP1AR
SCHEMBL29357262 0.78 ESR1 (1.00) ESR1ESR2TP53TDP1AR
SCHEMBL36509 0.78 ESR1 (1.00) ESR1ESR2TP53TDP1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143007-A1 MULTILAYER OBJECT AND RELEASE AGENT COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-05-11 — — US disclosed
CN-107077070-B Photosensitive resin composition, cured film, element provided with cured film, and method for manufacturing semiconductor device 东丽株式会社 2020-06-16 — — CN disclosed
US-9376383-B2 Isoprenyl compounds SIGNUM BIOSCIENCES, INC. (US) 2016-06-28 — — US disclosed
US-8426443-B2 Compounds which have activity at M1 receptor and their uses in medicine GLAXO GROUP LIMITED (GB) 2013-04-23 — — US disclosed
US-20120316196-A1 Compounds Which Have Activity at M1 Receptor and Their Uses in Medicine GLAXO GROUP LIMITED (GB) 2012-12-13 — — US disclosed
US-8299257-B2 Compounds which have activity at M1receptor and their uses in medicine GLAXO GROUP LIMITED (GB) 2012-10-30 — — US disclosed
US-8278328-B2 Compounds which have activity at M1 receptor and their uses in medicine GLAXO GROUP LIMITED (GB) 2012-10-02 — — US disclosed
US-20100210687-A1 Compounds which have activity at M1 receptor and their uses in medicine GLAXO GROUP LIMITED (GB) 2010-08-19 — — US disclosed
US-20100204272-A1 Compounds which have activity at M1 receptor and their uses in medicine Glaxo Group Limited a corporation 2010-08-12 — — US disclosed
EP-2194983-A1 COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE Glaxo Group Limited (GB) 2010-06-16 — — EP disclosed
EP-2194982-A1 COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE Glaxo Group Limited (GB) 2010-06-16 — — EP disclosed
US-7737291-B2 2,4,6,8-tetramethylcyclotetrasiloxane and stabilizer used as a material for thin film formation by chemical vapor deposition, or atomic layer deposition ADEKA CORPORATION (JP) 2010-06-15 — — US disclosed
US-7737291-B2 2,4,6,8-tetramethylcyclotetrasiloxane and stabilizer used as a material for thin film formation by chemical vapor deposition, or atomic layer deposition ADEKA CORPORATION (JP) 2010-06-15 — — US disclosed
WO-2009037294-A1 COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE GLAXO GROUP LIMITED (GB) 2009-03-26 — — WO disclosed
WO-2009037296-A1 COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE GLAXO GROUP LIMITED (GB) 2009-03-26 — — WO disclosed
US-20070232821-A1 Composition Containing Siloxane Compound and Phenol Compound ADEKA CORPORATION (JP) 2007-10-04 — — US disclosed
US-20070232821-A1 Composition Containing Siloxane Compound and Phenol Compound ADEKA CORPORATION (JP) 2007-10-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210687-A1 Compounds which have activity at M1 receptor and their uses in medicine CHRM1, CHRM2, CHRM5 ESR1 371/4885ESR2 592/4885TP53 1569/4885
US-20100204272-A1 Compounds which have activity at M1 receptor and their uses in medicine CHRM1, CHRM2, CHRM5 ESR1 371/4885ESR2 592/4885TP53 1569/4885
US-20120316196-A1 Compounds Which Have Activity at M1 Receptor and Their Uses in Medicine CHRM1, CHRM2, CHRM5 ESR1 371/4885ESR2 592/4885TP53 1569/4885
US-20070232821-A1 Composition Containing Siloxane Compound and Phenol Compound H1-0, CYP2S1, H1-4 ESR1 46/4885ESR2 283/4885TP53 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.