Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18572137 | 0.81 | TLR7 (0.36) | TLR7PDE5AAPPPDE10ASOS1 | |
| SCHEMBL22002181 | 0.81 | KDM4E (0.45) | TLR7PDE5AMEN1KMT2AALDH1A1 | |
| SCHEMBL28327449 | 0.72 | ALDH1A1 (0.46) | KMT2AALDH1A1GLAMAPTHPGD | |
| SCHEMBL27188777 | 0.71 | USP30 (0.63) | TLR7PDE5AAPPMEN1KMT2A | |
| SCHEMBL18572136 | 0.70 | SOS1 (0.38) | TLR7SOS1TRIM58ADORA2AHTR2B | |
| SCHEMBL22002290 | 0.70 | TLR7 (0.39) | TLR7APPPDE10ASOS1MEN1 | |
| SCHEMBL31542517 | 0.69 | APP (0.42) | TLR7PDE5AAPPMEN1KMT2A | |
| SCHEMBL29523642 | 0.68 | APP (0.55) | APPPDE10AMEN1KMT2AALDH1A1 | |
| SCHEMBL8890678 | 0.67 | TLR7 (0.64) | TLR7PDE5AAPPSOS1MEN1 | |
| SCHEMBL15067599 | 0.66 | PTGER4 (0.51) | GBA1BACE1UTS2RMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001133-A1 | PRMT5 INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2023-01-26 | — | — | WO | disclosed |