Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 12/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491279 | 0.85 | NPSR1 (0.47) | FFAR4FFAR1NPSR1POLBFBP1 | |
| SCHEMBL29901105 | 0.83 | CYP4F2 (0.46) | POLB | |
| SCHEMBL30159425 | 0.79 | BCL9 (0.44) | — | |
| SCHEMBL31392210 | 0.79 | FFAR1 (0.41) | FFAR4FFAR1FBP1 | |
| SCHEMBL29130747 | 0.78 | CA1 (0.42) | FFAR4FFAR1NPSR1POLBFBP1 | |
| SCHEMBL8796401 | 0.78 | NPSR1 (0.48) | FFAR4FFAR1NPSR1POLB | |
| SCHEMBL2492917 | 0.78 | ALDH1A1 (0.41) | NPSR1 | |
| SCHEMBL585512 | 0.74 | NPSR1 (0.48) | FFAR4FFAR1NPSR1POLB | |
| SCHEMBL543918 | 0.73 | TSHR (0.51) | POLB | |
| SCHEMBL14842322 | 0.73 | CYP1A2 (0.49) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110776-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2023-01-04 | — | — | EP | disclosed |