Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 19/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535792 | 1.00 | GSK3B (0.54) | GSK3BDYRK1AABL1 | |
| SCHEMBL20227778 | 0.82 | ABL1 (0.59) | GSK3BDYRK1AABL1 | |
| SCHEMBL30636341 | 0.81 | GSK3B (0.60) | GSK3BDYRK1AABL1 | |
| SCHEMBL28166698 | 0.81 | GSK3B (0.60) | GSK3BDYRK1AABL1 | |
| SCHEMBL479056 | 0.81 | NAMPT (0.43) | GSK3BDYRK1A | |
| SCHEMBL1258539 | 0.80 | ATR (0.47) | GSK3BDYRK1A | |
| SCHEMBL2924493 | 0.80 | CA12 (0.48) | — | |
| SCHEMBL30381612 | 0.80 | GSK3B (0.54) | GSK3BDYRK1AABL1 | |
| SCHEMBL25303717 | 0.80 | GSK3B (0.54) | GSK3BDYRK1AABL1 | |
| SCHEMBL10288086 | 0.79 | GSK3B (0.54) | GSK3BDYRK1AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076440-A1 | INHIBITORS OF ENL/AF9 YEATS | The Rockefeller University (US) | 2022-10-26 | — | — | EP | disclosed |