Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 4/20 | 0.46 |
| ▸ | PDE9A | O76083 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14718924 | 1.00 | HCAR2 (0.56) | HCAR2DAOCYP3A4PDE5APDE9A | |
| SCHEMBL14719290 | 0.87 | HCAR2 (0.48) | HCAR2DAOCYP3A4EGLN1PARP1 | |
| SCHEMBL16231965 | 0.85 | HTR2B (0.47) | HCAR2DAOEGLN1PARP1 | |
| SCHEMBL14719355 | 0.84 | LMNA (0.49) | DAOEGLN1 | |
| SCHEMBL14719472 | 0.83 | PARP1 (0.52) | HCAR2DAOPARP1 | |
| SCHEMBL14719140 | 0.83 | DAO (0.51) | DAOPARP1 | |
| SCHEMBL30107651 | 0.83 | DAO (0.51) | DAOPARP1 | |
| SCHEMBL14719553 | 0.83 | HCAR2 (0.56) | HCAR2DAOPARP1 | |
| SCHEMBL30107633 | 0.83 | HCAR2 (0.56) | HCAR2DAOPARP1 | |
| SCHEMBL14718571 | 0.80 | DAO (0.53) | DAOPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666526-A | Oral solid preparation | 武田药品工业株式会社 | 2023-01-31 | — | — | CN | disclosed |