Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 14/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CGAS | Q8N884 | 3/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160170 | 0.88 | GFER (0.40) | ALOX15MAPK1HSD17B10MEN1IKBKB | |
| SCHEMBL30159806 | 0.88 | GFER (0.40) | ALOX15MAPK1HSD17B10MEN1IKBKB | |
| SCHEMBL30240153 | 0.85 | ALOX15 (0.38) | ALOX15MAPK1HSD17B10CASP1CASP7 | |
| SCHEMBL24192045 | 0.84 | GFER (0.41) | ALOX15MAPK1HSD17B10CASP1CASP7 | |
| SCHEMBL24191951 | 0.84 | GFER (0.41) | ALOX15MAPK1HSD17B10CASP1CASP7 | |
| SCHEMBL150083 | 0.81 | HSD17B10 (0.58) | ALOX15MAPK1HSD17B10CASP1CASP7 | |
| SCHEMBL19279340 | 0.80 | BTK (0.55) | ALOX15MAPK1HSD17B10CASP1CASP7 | |
| SCHEMBL30159980 | 0.77 | HSD17B10 (0.41) | ALOX15MAPK1HSD17B10CASP1CASP7 | |
| SCHEMBL24192628 | 0.76 | GFER (0.35) | — | |
| SCHEMBL24192346 | 0.76 | GFER (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132910-A1 | KINASE INHIBITORS | GB002, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115667218-A | Kinase inhibitors | GB005股份有限公司 | 2023-01-31 | — | — | CN | disclosed |