Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017909 | 0.88 | ADORA3 (0.52) | ADORA2AADORA3ADORA1 | |
| SCHEMBL3026662 | 0.85 | ADORA1 (0.54) | ADORA2AADORA3ADORA1 | |
| SCHEMBL3022452 | 0.81 | ADORA3 (0.56) | ADORA2AADORA3ADORA1 | |
| SCHEMBL3030349 | 0.81 | ADORA1 (0.56) | ADORA2AADORA3ADORA1 | |
| SCHEMBL3030361 | 0.81 | ADORA1 (0.56) | ADORA2AADORA3ADORA1 | |
| SCHEMBL3026443 | 0.80 | ADORA3 (0.57) | ADORA2AADORA3ADORA1 | |
| SCHEMBL10156429 | 0.80 | ADORA2A (0.75) | ADORA2AADORA3ADORA1 | |
| SCHEMBL242489 | 0.79 | ADORA2A (0.74) | ADORA2AADORA3ADORA1 | |
| SCHEMBL242951 | 0.79 | ADORA2A (0.74) | ADORA2AADORA3ADORA1 | |
| SCHEMBL10156671 | 0.79 | ADORA3 (0.54) | ADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197914-A1 | Purine Derivatives as Adenosine Al Receptor Ligands | NOVARTIS AG (CH) | 2010-08-05 | — | — | US | disclosed |
| EP-2205601-A1 | PURINE DERIVATIVES AS ADENOSINE AL RECEPTOR LIGANDS | Novartis Ag (CH) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009050199-A1 | PURINE DERIVATIVES AS ADENOSINE AL RECEPTOR LIGANDS | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197914-A1 | Purine Derivatives as Adenosine Al Receptor Ligands | ADORA2A, ADORA1, ADORA3 | ADORA2A 1/4885ADORA3 3/4885ADORA1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.