Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.65 |
| ▸ | OTC | P00480 | 1/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 5/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | ARG2 | P78540 | 4/20 | 0.42 |
| ▸ | ARG1 | P05089 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL27968247 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL2143365 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL292022 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL8957537 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL11660904 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL714211 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL4954180 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL15022773 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL3516723 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 | |
| Arginine SCHEMBL27641260 | 1.00 | GSR (0.65) | GSROTCGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115590797-A | Firming and anti-wrinkle face cream containing bistort rhizome extract and preparation method thereof | 广东柏俐臣生物科技有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-109652397-B | Recombinant acetylated lysine arginine N-terminal protease and preparation method and application thereof | 北京蛋白质组研究中心 | 2022-02-25 | — | — | CN | claimed |
| CN-112957264-A | Freeze-dried powder based on beta-glucan as excipient and freeze-drying process thereof | 晟薇药业(上海)有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-110898372-B | Indoor formaldehyde purification method | 青岛广志光电科技有限公司 | 2021-03-19 | — | — | CN | claimed |
| WO-2020113552-A1 | RECOMBINANT ACETYLATED LYSINE ARGININE N-TERMINAL PROTEASE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 北京蛋白质组研究中心 | 2020-06-11 | — | — | WO | claimed |
| CN-110898372-A | Indoor formaldehyde purification method | 青岛广志光电科技有限公司 | 2020-03-24 | — | — | CN | claimed |
| CN-110433124-A | A kind of composition with moisturizing whitening wrinkle-removing effect | BAI DACHENG | 2019-11-12 | — | — | CN | claimed |
| CN-110004074-A | A kind of method and its special culture media using SILAC label mycobacterium smegmatis protein | 北京蛋白质组研究中心 | 2019-07-12 | — | — | CN | claimed |
| CN-109652397-A | A kind of recombination acetylated lysine arginine N-terminal protease and its preparation method and application | 北京蛋白质组研究中心 | 2019-04-19 | — | — | CN | claimed |
| CN-108101963-A | A kind of oligose peptide and preparation method thereof | 广西天昌投资有限公司 | 2018-06-01 | — | — | CN | claimed |
| EP-0998557-A2 | MODIFIED IMMUNOGENIC PNEUMOLYSIN, COMPOSITIONS AND THEIR USE AS VACCINES | NORTH AMERICAN VACCINE, INC. (CA) | 2000-05-10 | — | — | EP | claimed |
| EP-0932684-A2 | 3' GENOMIC PROMOTER REGION AND POLYMERASE GENE MUTATIONS RESPONSIBLE FOR ATTENUATION IN VIRUSES OF THE ORDER DESIGNATED MONONEGAVIRALES | AMERICAN CYANAMID COMPANY (US) | 1999-08-04 | — | — | EP | claimed |
| WO-1999003884-A2 | MODIFIED IMMUNOGENIC PNEUMOLYSIN, COMPOSITIONS AND THEIR USE AS VACCINES | NORTH AMERICAN VACCINE, INC. (US) | 1999-01-28 | — | — | WO | claimed |
| WO-1998053051-A1 | SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1998-11-26 | — | — | WO | claimed |
| WO-1998013501-A2 | 3' GENOMIC PROMOTER REGION AND POLYMERASE GENE MUTATIONS RESPONSIBLE FOR ATTENUATION IN VIRUSES OF THE ORDER DESIGNATED MONONEGAVIRALES | AMERICAN CYANAMID COMPANY (US) | 1998-04-02 | — | — | WO | claimed |
| US-5281721-A | Substituted carboxy- or carbonyl sulfide-containing 2-benzopyran or 2-benzothiopyran derivatives | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-01-25 | — | — | US | claimed |
| EP-0514359-A2 | Alkanoyl L-carnitine amides with aminoacids and pharmaceutical compositions containing same, for promoting regeneration of the nervous tissue, inhibiting neuronal degeneration, enhancing the processes of learning and memory, and for the treatment of coma | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-11-19 | — | — | EP | claimed |
| US-5093241-A | Chloramphenicol acetyltransferase linked to polypeptide | CELLTECH, LTD. (GB) | 1992-03-03 | — | — | US | claimed |
| EP-0443875-A2 | Vectors and compounds for expression of zymogen forms of human protein C | ELI LILLY AND COMPANY (US) | 1991-08-28 | — | — | EP | claimed |
| EP-0066458-A1 | Water-soluble benzothiazine dioxide salts | PFIZER INC. (US) | 1982-12-08 | — | — | EP | claimed |