Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 10/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042260 | 0.89 | SLC16A3 (0.53) | SLC16A3FOLH1ALDH1A1DHODHKDM4E | |
| SCHEMBL483196 | 0.89 | SLC16A3 (0.53) | SLC16A3FOLH1ALDH1A1DHODHKDM4E | |
| SCHEMBL466585 | 0.89 | SLC16A3 (0.53) | SLC16A3FOLH1ALDH1A1DHODHKDM4E | |
| SCHEMBL321495 | 0.89 | SLC16A3 (0.53) | SLC16A3FOLH1ALDH1A1DHODHKDM4E | |
| SCHEMBL480252 | 0.89 | SLC16A3 (0.53) | SLC16A3FOLH1ALDH1A1DHODHKDM4E | |
| SCHEMBL9770541 | 0.82 | SLC16A3 (0.52) | SLC16A3FOLH1ALDH1A1DHODHCYSLTR2 | |
| SCHEMBL9770470 | 0.80 | SLC16A3 (0.48) | SLC16A3FOLH1ALDH1A1DHODHTRPA1 | |
| SCHEMBL9770477 | 0.80 | SLC16A3 (0.48) | SLC16A3FOLH1ALDH1A1DHODHTRPA1 | |
| Propylene Glycol SCHEMBL27958334 | 0.79 | KAT8 (0.50) | SLC16A3FOLH1ALDH1A1CYSLTR2CYSLTR1 | |
| SCHEMBL30789020 | 0.78 | TDP1 (0.54) | SLC16A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419602-A1 | REACTIVE HOT-MELT ADHESIVE COMPOSITIONS BASED ON ALPHA-SILANE-TERMINATED ORGANIC POLYMERS | Kleiberit SE & Co. KG (DE) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023066902-A1 | REACTIVE HOT-MELT ADHESIVE COMPOSITIONS BASED ON ALPHA-SILANE-TERMINATED ORGANIC POLYMERS | KLEBCHEMIE M. G. BECKER GMBH & CO. KG (DE) | 2023-04-27 | — | — | WO | disclosed |
| EP-4139401-A1 | REACTIVE HOT-MELT ADHESIVE COMPOSITION BASED ON ALPHA-SILANE-TERMINATED ORGANIC POLYMERS | Klebchemie M.G. Becker GmbH & Co. KG (DE) | 2023-03-01 | — | — | EP | disclosed |