Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851282 | 1.00 | GPR119 (0.47) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL24851284 | 0.89 | GBA1 (0.51) | GPR119SMARCA2SMARCA4PBRM1GBA1 | |
| SCHEMBL3882127 | 0.86 | SUV39H2 (0.44) | GPR119CKS1BSKP1SKP2MEN1 | |
| SCHEMBL24851280 | 0.85 | SMARCA2 (0.45) | GPR119SMARCA2SMARCA4PBRM1ABCB1 | |
| SCHEMBL24851765 | 0.84 | GBA1 (0.51) | GPR119CKS1BSKP1SKP2GBA1 | |
| SCHEMBL18153359 | 0.84 | GBA1 (0.51) | GPR119CKS1BSKP1SKP2GBA1 | |
| SCHEMBL18162447 | 0.83 | GBA1 (0.50) | GPR119CKS1BSKP1SKP2GBA1 | |
| SCHEMBL30162196 | 0.83 | GBA1 (0.50) | GPR119CKS1BSKP1SKP2GBA1 | |
| SCHEMBL24851167 | 0.83 | GBA1 (0.50) | GPR119CKS1BSKP1SKP2GBA1 | |
| SCHEMBL24851944 | 0.82 | GPR119 (0.43) | GPR119CKS1BSKP1SKP2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |