Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24842790 | 1.00 | LMNA (0.39) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL11557183 | 0.84 | KDR (0.39) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL24841515 | 0.80 | ADRB3 (0.41) | SMN1; SMN2TMEM97GBA1 | |
| SCHEMBL24841508 | 0.79 | HDAC3 (0.36) | — | |
| SCHEMBL24841511 | 0.79 | HDAC3 (0.36) | — | |
| SCHEMBL24841242 | 0.78 | LMNA (0.37) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL13761349 | 0.76 | LMNA (0.36) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL28206628 | 0.74 | LMNA (0.36) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL24841259 | 0.74 | LMNA (0.34) | LMNASMN1; SMN2ADORA1ALDH1A1GLA | |
| SCHEMBL13761347 | 0.72 | LMNA (0.35) | LMNASMN1; SMN2ADORA1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023277517-A1 | ACYCLIC NUCLEIC ACID MIMIC COMPRISING PENTACYCLIC BASE | 동아대학교 산학협력단 | 2023-01-05 | — | — | WO | disclosed |