Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428589 | 0.86 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL31428848 | 0.86 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL31428748 | 0.85 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL31428731 | 0.82 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL30163547 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL31429081 | 0.81 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL31428963 | 0.80 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL31428792 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL30163485 | 0.80 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL31428790 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1SMN1; SMN2TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |