Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24858035 | 1.00 | KMT2A (0.41) | KMT2AMEN1LMNAAGTR1HTT | |
| SCHEMBL30211271 | 0.79 | ATR (0.54) | LMNARAB9APOLBATRKDM4E | |
| SCHEMBL1330551 | 0.79 | ATR (0.54) | LMNARAB9APOLBATRKDM4E | |
| SCHEMBL1855481 | 0.77 | HPGD (0.49) | RAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL23326783 | 0.76 | KDM4E (0.43) | LMNAHTTRAB9AATRKDM4E | |
| SCHEMBL30605221 | 0.75 | KDM4E (0.37) | KMT2ALMNARAB9ACYP1A2CYP2C9 | |
| SCHEMBL1462341 | 0.74 | KDM4E (0.44) | KMT2ALMNARAB9APOLBATR | |
| SCHEMBL473869 | 0.74 | KDM4E (0.63) | KMT2AMEN1LMNARAB9AKDM4E | |
| SCHEMBL29418893 | 0.74 | KDM4E (0.63) | KMT2AMEN1LMNARAB9AKDM4E | |
| SCHEMBL27096669 | 0.73 | KDM4E (0.43) | LMNAHTTRAB9AKDM4EASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274397-A1 | CDK2 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海拓界生物医药科技有限公司 | 2023-01-05 | — | — | WO | disclosed |