Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366742 | 1.00 | TDP1 (0.46) | TDP1CYP3A4DRD1TSHRACHE | |
| SCHEMBL30142870 | 1.00 | TDP1 (0.46) | TDP1CYP3A4DRD1TSHRACHE | |
| SCHEMBL12394364 | 0.98 | TDP1 (0.44) | TDP1CYP3A4DRD1TSHRACHE | |
| SCHEMBL9267935 | 0.98 | TDP1 (0.44) | TDP1CYP3A4DRD1TSHRACHE | |
| SCHEMBL10805185 | 0.98 | TDP1 (0.44) | TDP1CYP3A4DRD1TSHRACHE | |
| Hydrochloric Acid SCHEMBL3452761 | 0.96 | CYP3A4 (0.42) | TDP1CYP3A4DRD1TSHRACHE | |
| SCHEMBL9490734 | 0.94 | DRD1 (0.41) | TDP1CYP3A4DRD1TSHRACHE | |
| Perchlorate SCHEMBL9484540 | 0.92 | DRD1 (0.40) | TDP1CYP3A4DRD1TSHRACHE | |
| Perchlorate SCHEMBL10466526 | 0.92 | DRD1 (0.40) | TDP1CYP3A4DRD1TSHRACHE | |
| SCHEMBL19266729 | 0.91 | DRD1 (0.39) | TDP1CYP3A4DRD1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856738-B1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | QUIM SINTETICA S A (ES) | 2025-03-19 | — | — | EP | claimed |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | Química Sintética, S.A. (ES) | 2022-10-11 | — | — | US | claimed |
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2022-02-03 | — | — | US | claimed |
| CN-105899492-B | Process for preparing pyrimidylcyclopentane compounds | 豪夫迈·罗氏有限公司 | 2021-08-24 | — | — | CN | claimed |
| EP-3856738-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2021-08-04 | — | — | EP | claimed |
| WO-2020064818-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | Química Sintética, S.A. (ES) | 2020-04-02 | — | — | WO | claimed |
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | claimed |
| US-8436181-B2 | Production process of optically active 3-quinuclidinol derivative | NIPPON SODA CO., LTD. (JP) | 2013-05-07 | — | — | US | claimed |
| EP-1840116-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-HYDROXY-ALPHA-AMINOCARBOXYLIC ACID DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2012-10-03 | — | — | EP | claimed |
| US-7902110-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | claimed |
| EP-0974590-A1 | Process for the preparation of chiral lactones by asymetrical hydrogenation | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-26 | — | — | EP | claimed |
| US-5929265-A | REACTING 2-NORBORNENE AND ANILINE TO YIELD 2-PHENYLAMINO-NORBORNANE; DURABILITY; HIGH OPTICAL YIELDS; KINETICS; ALSO EFFECTING CYCLIZATION AS WHEN PRODUCING INDOLINES FROM ORTHO-ALKENYL-SUBSTITUTED ANILINES | LONZA AG | 1999-07-27 | — | — | US | claimed |
| US-5902882-A | ASYMMETRICALLY HYDROGENATING AN AZEPINE COMPOUND IN THE PRESENCE OF A RUTHENIUM-DIPHOSPHINE COMPLEX CATALYST | HOFFMANN-LA ROCHE INC. (US) | 1999-05-11 | — | — | US | claimed |
| EP-0909762-A2 | Binuclear Iridium(I) phosphine complexes and their use as catalysts for the asymmetric hydroamination of olefins | LONZA A.G. (CH) | 1999-04-21 | — | — | EP | claimed |
| EP-0802190-A1 | Process and intermediates for preparing azepines | F. HOFFMANN-LA ROCHE AG (CH) | 1997-10-22 | — | — | EP | claimed |
| EP-0492401-B1 | Asymmetric hydrogenation | CIBA GEIGY AG (CH) | 1996-01-24 | — | — | EP | claimed |
| EP-0257411-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE ENAMINES OR THE CORRESPONDING ALDEHYDES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-25 | — | — | EP | claimed |
| US-4861890-A | Isomerization | HOFFMANN-LA ROCHE INC. (US) | 1989-08-29 | — | — | US | claimed |
| EP-0104376-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINES AND ENAMINES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-05-06 | — | — | EP | claimed |
| EP-0104375-A1 | Phosphorus-containing biphenyl derivatives and their use in asymmetric hydrogenation and enatioselective hydrogen shifts | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-04-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033365-A1 | PROCESS FOR THE PREPARATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONIST | S1PR1, S1PR4, S1PR3 | TDP1 2234/4885CYP3A4 1653/4885DRD1 1479/4885 |
| US-11465977-B2 | Process for the preparation of sphingosine-1-phosphate receptor agonist | S1PR1, S1PR4, S1PR3 | TDP1 2234/4885CYP3A4 1653/4885DRD1 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.