Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.30 |
| ▸ | CD44 | P16070 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366742 | 0.94 | TDP1 (0.46) | DRD1CYP3A4TDP1MYCESR1 | |
| SCHEMBL301645 | 0.94 | TDP1 (0.46) | DRD1CYP3A4TDP1MYCESR1 | |
| SCHEMBL30142870 | 0.94 | TDP1 (0.46) | DRD1CYP3A4TDP1MYCESR1 | |
| SCHEMBL12394364 | 0.92 | TDP1 (0.44) | DRD1CYP3A4TDP1MYCESR1 | |
| SCHEMBL10805185 | 0.92 | TDP1 (0.44) | DRD1CYP3A4TDP1MYCESR1 | |
| SCHEMBL9267935 | 0.92 | TDP1 (0.44) | DRD1CYP3A4TDP1MYCESR1 | |
| Hydrochloric Acid SCHEMBL3452761 | 0.90 | CYP3A4 (0.42) | DRD1CYP3A4TDP1MYCESR1 | |
| Perchlorate SCHEMBL9484540 | 0.87 | DRD1 (0.40) | DRD1CYP3A4TDP1MYCESR1 | |
| Perchlorate SCHEMBL10466526 | 0.87 | DRD1 (0.40) | DRD1CYP3A4TDP1MYCESR1 | |
| SCHEMBL19266729 | 0.85 | DRD1 (0.39) | DRD1CYP3A4TDP1MYCESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269395-B1 | RUTHENIUM-PHOSPHINE COMPLEX CATALYSTS | Takasago International Corporation (JP) | 1993-02-17 | — | — | EP | claimed |
| EP-0269395-B1 | RUTHENIUM-PHOSPHINE COMPLEX CATALYSTS | Takasago International Corporation (JP) | 1993-02-17 | — | — | EP | disclosed |
| US-4764629-A | Ruthenium-phosphine complex | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1988-08-16 | — | — | US | disclosed |