Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.48 |
| ▸ | ESR1 | P03372 | 10/20 | 0.48 |
| ▸ | AR | P10275 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24743942 | 1.00 | ESR2 (0.48) | ESR2ESR1ARCYP3A4HPGD | |
| SCHEMBL26817473 | 0.85 | AR (0.47) | ESR2ESR1ARCYP3A4HPGD | |
| SCHEMBL16122295 | 0.78 | AR (0.36) | ARCYP3A4HPGDTSHRHSD17B10 | |
| SCHEMBL24743943 | 0.77 | AR (0.38) | ARRAPGEF3RAPGEF4 | |
| SCHEMBL25402309 | 0.77 | AR (0.43) | ESR2ESR1ARCYP3A4HPGD | |
| SCHEMBL22468693 | 0.76 | AR (0.48) | ESR2ESR1ARCYP3A4HPGD | |
| SCHEMBL29448092 | 0.76 | AR (0.48) | ESR2ESR1ARCYP3A4HPGD | |
| Cyanate SCHEMBL30541970 | 0.75 | ESR1 (0.52) | ESR2ESR1ARCYP3A4HPGD | |
| Bisphenol A SCHEMBL486701 | 0.72 | ESR1 (0.76) | ESR2ESR1ARCYP3A4HPGD | |
| Bisphenol A SCHEMBL2335786 | 0.72 | ESR1 (0.76) | ESR2ESR1ARCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226349-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | ESSA PHARMA, INC. (CA) | 2022-10-27 | — | — | WO | disclosed |