Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PDXK | O00764 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.32 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898551 | 1.00 | RECQL (0.39) | RECQLLMNAKDM4EMAPTTP53 | |
| SCHEMBL24743981 | 0.81 | KMT2A (0.33) | BUB1 | |
| SCHEMBL11973378 | 0.79 | BUB1 (0.37) | LMNAKDM4EMAPTBUB1SMN1; SMN2 | |
| SCHEMBL22972189 | 0.79 | LOXL2 (0.44) | BUB1LOXL2 | |
| SCHEMBL15228960 | 0.79 | BUB1 (0.32) | BUB1 | |
| SCHEMBL3936657 | 0.78 | KDM4E (0.41) | RECQLLMNAKDM4EMAPTTP53 | |
| SCHEMBL844264 | 0.78 | RECQL (0.42) | RECQLLMNAKDM4EMAPTTP53 | |
| SCHEMBL30673110 | 0.78 | RECQL (0.42) | RECQLLMNAKDM4EMAPTTP53 | |
| Hydrochloric Acid SCHEMBL18695326 | 0.78 | LOXL2 (0.42) | BUB1LOXL2 | |
| SCHEMBL26618184 | 0.77 | KDM4E (0.42) | LMNAKDM4EMAPTTSHRBUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2022226349-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | ESSA PHARMA, INC. (CA) | 2022-10-27 | — | — | WO | disclosed |