SCHEMBL30165146

SCHEMBL30165146

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CCN)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.48
▸ GRIN3B O60391 1/20 0.48
▸ GRIN1 Q05586 1/20 0.48
▸ GRIN2A Q12879 1/20 0.48
▸ GRIN2B Q13224 1/20 0.48
▸ GRIN2C Q14957 1/20 0.48
▸ GRIN3A Q8TCU5 1/20 0.48
▸ F2 P00734 5/20 0.48
▸ GLP1R P43220 9/20 0.45
▸ BACE1 P56817 1/20 0.44
▸ CRHR1 P34998 1/20 0.44
▸ CRHR2 Q13324 1/20 0.44
▸ MDM4 O15151 1/20 0.43
▸ MDM2 Q00987 1/20 0.43
▸ CALCR P30988 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30165147 0.96 F2 (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30165207 0.96 F2 (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30165209 0.96 GRIN2D (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30165148 0.94 GRIN2D (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30165255 0.94 GRIN2D (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30165278 0.93 GLP1R (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30165162 0.93 CTSD (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30165174 0.92 GLP1R (0.50) GLP1RCRHR1CRHR2CALCR
SCHEMBL30165145 0.92 GLP1R (0.50) GLP1RCRHR1CRHR2CALCR
SCHEMBL30165190 0.91 GLP1R (0.48) F2GLP1RBACE1CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115640-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF INNERSE (ZHUHAI) PHARMACEUTICAL CO., LTD. (CN) 2025-04-10 — — US claimed
EP-4378949-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF Innerse (Zhuhai) Pharmaceutical Co., Ltd. (CN) 2024-06-05 — — EP claimed
WO-2023006083-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF 英纳氏(珠海)药业有限公司 2023-02-02 — — WO claimed
US-20250115640-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF INNERSE (ZHUHAI) PHARMACEUTICAL CO., LTD. (CN) 2025-04-10 — — US disclosed
CN-113735938-B Neuroprotective polypeptide compound and application thereof 英纳氏(珠海)药业有限公司 2024-11-08 — — CN disclosed
EP-4378949-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF Innerse (Zhuhai) Pharmaceutical Co., Ltd. (CN) 2024-06-05 — — EP disclosed
WO-2023006083-A1 NEUROPROTECTIVE POLYPEPTIDE COMPOUND AND APPLICATION THEREOF 英纳氏(珠海)药业有限公司 2023-02-02 — — WO disclosed
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