Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.38 |
| ▸ | FPR2 | P25090 | 8/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23884144 | 1.00 | SCN9A (0.38) | SCN9AFPR2EPHX2ENPP3CA12 | |
| SCHEMBL23884195 | 0.86 | MAPT (0.39) | SCN9AFPR2EPHX2CYP1A2CYP2C19 | |
| SCHEMBL30165318 | 0.86 | MAPT (0.39) | SCN9AFPR2EPHX2CYP1A2CYP2C19 | |
| SCHEMBL23907992 | 0.75 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL23884164 | 0.74 | SCN9A (0.32) | SCN9A | |
| SCHEMBL30165244 | 0.74 | SCN9A (0.32) | SCN9A | |
| SCHEMBL30165200 | 0.73 | CYP3A4 (0.33) | — | |
| SCHEMBL30361601 | 0.72 | SCN9A (0.41) | SCN9AFPR2CYP1A2CYP2C19F2 | |
| SCHEMBL30165226 | 0.68 | ALDH1A1 (0.35) | EPHX2 | |
| SCHEMBL30165307 | 0.67 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125845-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | Southern Research Institute (US) | 2023-02-08 | — | — | EP | disclosed |