Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592694 | 1.00 | POLB (0.61) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL30344008 | 0.78 | POLB (0.64) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL1180653 | 0.78 | POLB (0.64) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL29771433 | 0.76 | POLB (1.00) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL153365 | 0.76 | POLB (1.00) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL29787117 | 0.76 | POLB (1.00) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL31210085 | 0.76 | POLB (0.61) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL10879830 | 0.76 | POLB (0.61) | POLBLMNAMAPTHTTALDH1A1 | |
| SCHEMBL22879339 | 0.74 | MEN1 (0.62) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8516057 | 0.73 | POLB (0.57) | POLBLMNAMAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126991-A1 | STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | Dow Global Technologies LLC (US) | 2023-02-08 | — | — | EP | disclosed |