Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344008 | 1.00 | POLB (0.64) | POLBKDM4EALDH1A1P2RX4ATM | |
| SCHEMBL2424796 | 0.89 | P2RX4 (0.69) | POLBKDM4EALDH1A1P2RX4LMNA | |
| SCHEMBL29547258 | 0.83 | MAOA (0.53) | POLBKDM4EALDH1A1P2RX4LMNA | |
| SCHEMBL20581865 | 0.83 | MAOA (0.53) | POLBKDM4EALDH1A1P2RX4LMNA | |
| SCHEMBL28328560 | 0.83 | LMNA (0.56) | POLBKDM4EALDH1A1P2RX4LMNA | |
| SCHEMBL783425 | 0.83 | TSPO (0.52) | POLBKDM4EALDH1A1P2RX4LMNA | |
| SCHEMBL20696079 | 0.83 | POLB (0.47) | POLBKDM4EALDH1A1P2RX4ATM | |
| SCHEMBL20699878 | 0.83 | POLB (0.47) | POLBKDM4EALDH1A1P2RX4ATM | |
| SCHEMBL1120303 | 0.83 | POLB (0.47) | POLBKDM4EALDH1A1P2RX4LMNA | |
| SCHEMBL872109 | 0.79 | P2RX4 (0.81) | POLBALDH1A1P2RX4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245599-B | Novel 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication | ACHILLION PHARMACEUTICALS INC | 2014-05-14 | — | — | CN | claimed |
| US-12109263-B2 | Integrin agonists or activating compounds and methods for making and using same | 7 HILLS PHARMA INC. | 2024-10-08 | — | — | US | disclosed |
| US-20240199765-A1 | METHOD OF PULPING COTTON-BASED RAW MATERIAL | CHEMIEFASER LENZING AG (AT) | 2024-06-20 | — | — | US | disclosed |
| US-11939405-B2 | Method of pulping cotton-based raw material | LENZING AG (AT) | 2024-03-26 | — | — | US | disclosed |
| EP-3559341-B1 | METHOD OF PULPING COTTON-BASED RAW MATERIAL | CHEMIEFASER LENZING AG (AT) | 2024-02-28 | — | — | EP | disclosed |
| US-20220118086-A1 | INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME | 7 Hills Pharma LLC (US) | 2022-04-21 | — | — | US | disclosed |
| US-20210130501-A1 | METHOD OF PULPING COTTON-BASED RAW MATERIAL | LENZING AG (AT) | 2021-05-06 | — | — | US | disclosed |
| EP-3559341-A1 | METHOD OF PULPING COTTON-BASED RAW MATERIAL | Lenzing Aktiengesellschaft (AT) | 2019-10-30 | — | — | EP | disclosed |
| CN-110088393-A | By the method for cotton based raw material slurrying | 连津格股份公司 | 2019-08-02 | — | — | CN | disclosed |
| WO-2018115428-A1 | METHOD OF PULPING COTTON-BASED RAW MATERIAL | LENZING AKTIENGESELLSCHAFT (AT) | 2018-06-28 | — | — | WO | disclosed |
| CN-102459172-A | Tetracyclic compounds | CHUGAI PHARMACEUTICAL CO LTD | 2012-05-16 | — | — | CN | disclosed |
| WO-2012006419-A2 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20110046378-A1 | Novel Imaging Agents for Detecting Neurological Dysfunction | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20090117040-A1 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | MAX-DELBRUG-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2009-05-07 | — | — | US | disclosed |
| EP-0815080-B1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-06-16 | — | — | EP | disclosed |
| CN-1263092-A | Carboxylic compound and its preparation method and application | LANZHOU CHEM PHYS INST (CN) | 2000-08-16 | — | — | CN | disclosed |
| US-6002009-A | Di-substituted 1,4-piperidine esters and amides having 5-HT4 antagonistic activity | BOEHRINGER INGELHEIM ITALIA, S.P.A. (IT) | 1999-12-14 | — | — | US | disclosed |
| CN-1178524-A | Di-substituted 1, 4 -piperidine esters and amides having 5-HT4 antagonistic activity | BOEHRINGER INGELHEIM ITALIA (IT) | 1998-04-08 | — | — | CN | disclosed |
| EP-0815080-A1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT 4? ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996028424-A1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA S.P.A. (IT) | 1996-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118086-A1 | INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME | ICOS, CD47, CD274 | POLB 3911/4885KDM4E 1595/4885ALDH1A1 398/4885 |
| US-20110046378-A1 | Novel Imaging Agents for Detecting Neurological Dysfunction | FABP7, SLC18A3, TSPO | POLB 4090/4885KDM4E 4258/4885ALDH1A1 3189/4885 |
| US-20090117040-A1 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases | APP, PSEN2, PSEN1 | POLB 2424/4885KDM4E 4827/4885ALDH1A1 3112/4885 |
| US-12109263-B2 | Integrin agonists or activating compounds and methods for making and using same | ICOS, CD47, CD274 | POLB 3911/4885KDM4E 1595/4885ALDH1A1 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.