Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.46 |
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958043 | 0.84 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL30160692 | 0.79 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL30160980 | 0.78 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL5112706 | 0.77 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL5114322 | 0.76 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL5406790 | 0.76 | CHRNB2 (0.55) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL6626222 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL5111871 | 0.74 | KCNH2 (0.45) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL3579577 | 0.73 | CHRNB4 (0.55) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 | |
| SCHEMBL6625740 | 0.71 | CHRNB4 (0.49) | CHRNB2CHRNA4CHRNA1CHRNA7CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |