Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962247 | 1.00 | NPC1 (0.46) | NPC1SMN1; SMN2ALOX5ADORA3ADORA2A | |
| SCHEMBL28928989 | 0.90 | NPC1 (0.46) | NPC1SMN1; SMN2ALOX5ADORA3ADORA2A | |
| SCHEMBL30166002 | 0.90 | NPC1 (0.46) | NPC1SMN1; SMN2ALOX5ADORA3ADORA2A | |
| SCHEMBL28929042 | 0.88 | L3MBTL1 (0.46) | NPC1SMN1; SMN2ADORA3ADORA2ATOP1 | |
| SCHEMBL30166013 | 0.88 | L3MBTL1 (0.46) | NPC1SMN1; SMN2ADORA3ADORA2ATOP1 | |
| SCHEMBL30166004 | 0.83 | PTPN1 (0.43) | NPC1SMN1; SMN2ADORA3MAPTMEN1 | |
| SCHEMBL28929020 | 0.83 | PTPN1 (0.43) | NPC1SMN1; SMN2ADORA3MAPTMEN1 | |
| SCHEMBL28928987 | 0.81 | CYP1A2 (0.50) | NPC1SMN1; SMN2ADORA3TOP1MAPT | |
| SCHEMBL30166020 | 0.81 | CYP1A2 (0.50) | NPC1SMN1; SMN2ADORA3TOP1MAPT | |
| SCHEMBL28928978 | 0.79 | CES1 (0.42) | NPC1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583876-B | Phenyl naphthacene ketone compound and preparation method and application thereof | 深圳技术大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-115583876-A | Phenyl-naphthalenepophenone compounds, preparation method and application thereof | 深圳技术大学 | 2023-01-10 | — | — | CN | disclosed |