Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929462 | 1.00 | ADORA3 (0.48) | ADORA3ADORA2ATOP1BRD4ALOX5 | |
| SCHEMBL30166001 | 0.87 | ADORA3 (0.48) | ADORA3ADORA2ATOP1BRD4SMN1; SMN2 | |
| SCHEMBL28929009 | 0.87 | ADORA3 (0.48) | ADORA3ADORA2ATOP1BRD4SMN1; SMN2 | |
| SCHEMBL28929039 | 0.81 | ADORA3 (0.47) | ADORA3ADORA2ABRD4ALOX5SMN1; SMN2 | |
| 4-Methoxy-1H-Phenalen-1-One SCHEMBL8370893 | 0.81 | TOP1 (0.51) | TOP1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28928955 | 0.80 | KDM4E (0.46) | ADORA3TOP1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL30165983 | 0.80 | KDM4E (0.46) | ADORA3TOP1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL30165999 | 0.80 | CYP3A4 (0.46) | ADORA3TOP1MAPTALDH1A1CYP1A1 | |
| SCHEMBL28929045 | 0.80 | CYP3A4 (0.46) | ADORA3TOP1MAPTALDH1A1CYP1A1 | |
| SCHEMBL28928958 | 0.79 | ADORA3 (0.46) | ADORA3ADORA2ABRD4ALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583876-B | Phenyl naphthacene ketone compound and preparation method and application thereof | 深圳技术大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-115583876-A | Phenyl-naphthalenepophenone compounds, preparation method and application thereof | 深圳技术大学 | 2023-01-10 | — | — | CN | disclosed |