SCHEMBL30166136

SCHEMBL30166136

O=C(c1ccccc1)c1ccc(Sc2ccc3c(c2)CCC3=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.44
MCL1 Q07820 1/20 0.44
GRM5 P41594 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
SRD5A2 P31213 2/20 0.43
SRD5A1 P18405 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
CYP2C8 P10632 1/20 0.42
CYP2C9 P11712 1/20 0.42
MAPK14 Q16539 5/20 0.42
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HSD17B1 P14061 1/20 0.40
PTPRC P08575 1/20 0.40
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176410 1.00 BCL2 (0.44) BCL2MCL1GRM5ALDH1A1HPGD
SCHEMBL316294 0.88 GRM5 (0.54) BCL2MCL1GRM5MAOAMAOB
SCHEMBL315261 0.79 GRM5 (0.56) BCL2MCL1GRM5MAOAMAOB
SCHEMBL385623 0.78 ALDH1A1 (0.67) ALDH1A1HPGDSRD5A2MAPK14ATM
SCHEMBL21506865 0.78 ALDH1A1 (0.67) ALDH1A1HPGDSRD5A2MAPK14ATM
SCHEMBL9624909 0.77 ATM (0.61) ALDH1A1HPGDSRD5A2CYP2C9MAPK14
SCHEMBL17828245 0.76 ALDH1A1 (0.67) ALDH1A1HPGDSRD5A2MAPK14HSD17B10
SCHEMBL6787662 0.76 ALDH1A1 (0.67) ALDH1A1HPGDSRD5A2MAPK14HSD17B10
SCHEMBL3282737 0.76 HPGD (0.69) ALDH1A1HPGDSRD5A2MAOAMAOB
SCHEMBL17828242 0.76 ALDH1A1 (0.67) ALDH1A1HPGDSRD5A2MAPK14HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117545783-A Curable composition, method for producing cured product, film, optical element, image sensor, solid-state imaging element, image display device, and radical polymerization initiator 富士胶片株式会社 2024-02-09 CN disclosed
WO-2023026884-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT, FILM, OPTICAL ELEMENT, IMAGE SENSOR, SOLID STATE IMAGE SENSOR, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR 富士フイルム株式会社 2023-03-02 WO disclosed