Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529138 | 1.00 | ROCK2 (0.51) | ROCK2 | |
| SCHEMBL22396342 | 0.83 | ROCK2 (0.60) | ROCK2 | |
| SCHEMBL30356981 | 0.83 | ROCK2 (0.60) | ROCK2 | |
| SCHEMBL23529060 | 0.83 | ROCK2 (0.52) | ROCK2 | |
| SCHEMBL22396229 | 0.82 | ROCK2 (0.57) | ROCK2 | |
| SCHEMBL23529070 | 0.82 | ROCK2 (0.51) | ROCK2 | |
| SCHEMBL21490345 | 0.81 | ROCK2 (0.53) | ROCK2 | |
| SCHEMBL29442924 | 0.81 | ROCK2 (0.53) | ROCK2 | |
| SCHEMBL21490339 | 0.79 | ROCK2 (0.58) | ROCK2 | |
| SCHEMBL29442943 | 0.79 | ROCK2 (0.58) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704121-B1 | DIAZASPIRO ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-12-21 | — | — | EP | disclosed |