Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | MAPKAPK5 | Q8IW41 | 3/20 | 0.40 |
| ▸ | TTK | P33981 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24104736 | 1.00 | PTK6 (0.41) | PTK6MAPKAPK5TTKUSP2IGF1R | |
| SCHEMBL25170919 | 0.98 | PTK6 (0.42) | PTK6MAPKAPK5TTKUSP2IGF1R | |
| SCHEMBL25167794 | 0.86 | PTK6 (0.46) | PTK6MAPKAPK5TTKUSP2IGF1R | |
| SCHEMBL30168204 | 0.86 | PTK6 (0.46) | PTK6MAPKAPK5TTKUSP2IGF1R | |
| SCHEMBL24105218 | 0.84 | PTK6 (0.47) | PTK6MAPKAPK5TTKALDH1A1AURKA | |
| SCHEMBL30168133 | 0.82 | PTK6 (0.42) | PTK6MAPKAPK5TTKIGF1RALDH1A1 | |
| SCHEMBL22124679 | 0.82 | TTK (0.44) | PTK6MAPKAPK5TTKBRAF | |
| SCHEMBL22139065 | 0.81 | MAPKAPK5 (0.54) | PTK6MAPKAPK5TTK | |
| SCHEMBL22122845 | 0.81 | TTK (0.50) | PTK6MAPKAPK5TTK | |
| Hydrochloric Acid SCHEMBL22123544 | 0.81 | TTK (0.44) | PTK6MAPKAPK5TTKBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |