Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25167794 | 0.88 | PTK6 (0.46) | PTK6TTKMAPTRXFP1ALDH1A1 | |
| SCHEMBL30168204 | 0.88 | PTK6 (0.46) | PTK6TTKMAPTRXFP1ALDH1A1 | |
| SCHEMBL24105218 | 0.86 | PTK6 (0.47) | PTK6TTKALDH1A1EGFRERBB2 | |
| SCHEMBL25170919 | 0.83 | PTK6 (0.42) | PTK6TTKMAPTRXFP1POLB | |
| SCHEMBL22139065 | 0.83 | MAPKAPK5 (0.54) | PTK6TTKEGFRKDRMAPKAPK5 | |
| SCHEMBL30172072 | 0.82 | TTK (0.52) | PTK6TTKMAPKAPK5 | |
| SCHEMBL22122908 | 0.82 | TTK (0.52) | PTK6TTKMAPKAPK5 | |
| SCHEMBL24104736 | 0.82 | PTK6 (0.41) | PTK6TTKMAPTRXFP1ALDH1A1 | |
| SCHEMBL24105205 | 0.82 | KDR (0.48) | PTK6MAPTNPSR1ALDH1A1EGFR | |
| SCHEMBL30167861 | 0.82 | PTK6 (0.41) | PTK6TTKMAPTRXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |