Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 10/20 | 0.57 |
| ▸ | CDK2 | P24941 | 9/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.57 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.57 |
| ▸ | CDK9 | P50750 | 7/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.57 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.57 |
| ▸ | CCND3 | P30281 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 1/20 | 0.57 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 3/20 | 0.53 |
| ▸ | DCLK1 | O15075 | 3/20 | 0.53 |
| ▸ | JAK3 | P52333 | 3/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7659966 | 0.77 | CDK1 (0.58) | CDK1CDK2FLT3JAK3PDPK1 | |
| SCHEMBL3026520 | 0.77 | CDK2 (0.60) | CDK1CDK2CDK5CDK5R1FLT3 | |
| SCHEMBL27152320 | 0.76 | CDK1 (0.60) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL30847388 | 0.76 | CDK1 (0.60) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL27109966 | 0.76 | CDK1 (0.60) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3023246 | 0.75 | TNNI3K (0.47) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL1632161 | 0.75 | CDK1 (0.59) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL4005818 | 0.75 | JAK3 (0.71) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL1633964 | 0.75 | SYK (0.57) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3620313 | 0.74 | CDK1 (0.55) | CDK1CDK2CCNT1CCNB1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | CDK1 60/4885CDK2 137/4885CCNT1 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.