Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.55 |
| ▸ | CDK2 | P24941 | 8/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.55 |
| ▸ | CDK9 | P50750 | 7/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.55 |
| ▸ | CDK7 | P50613 | 4/20 | 0.55 |
| ▸ | CCNH | P51946 | 4/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.55 |
| ▸ | JAK3 | P52333 | 9/20 | 0.55 |
| ▸ | JAK1 | P23458 | 8/20 | 0.55 |
| ▸ | SYK | P43405 | 4/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.50 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613897 | 0.85 | CDK1 (0.57) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3620405 | 0.84 | CDK1 (0.55) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3623248 | 0.82 | SYK (0.63) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3619732 | 0.82 | CDK2 (0.53) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3621559 | 0.79 | CDK2 (0.54) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3622052 | 0.79 | CDK2 (0.54) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3622441 | 0.78 | IKBKB (0.59) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3619870 | 0.77 | CDK1 (0.54) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3621478 | 0.77 | CDK2 (0.54) | CDK1CDK2CCNT1CCNB1CDK9 | |
| SCHEMBL3607870 | 0.77 | JAK1 (0.50) | CDK1CDK2CCNT1CCNB1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093776-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-04-15 | — | — | US | disclosed |
| US-20100093776-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-04-15 | — | — | US | disclosed |
| US-20100093776-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093776-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | CDK1 3769/4885CDK2 3078/4885CCNT1 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.