Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866085 | 1.00 | HSD17B10 (0.59) | HSD17B10KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL76351 | 0.95 | KMT2A (0.58) | HSD17B10KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL5425961 | 0.94 | KMT2A (0.57) | HSD17B10KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL17979899 | 0.87 | HSD17B10 (0.59) | HSD17B10KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL2760313 | 0.85 | HSD17B10 (0.57) | HSD17B10KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL12070446 | 0.83 | HSD17B10 (0.55) | HSD17B10KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL25307241 | 0.82 | HSD17B10 (0.58) | HSD17B10KMT2AMAPTGAAMEN1 | |
| SCHEMBL3750305 | 0.81 | MAPT (0.46) | HSD17B10KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL5631995 | 0.81 | MAPT (0.57) | HSD17B10KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL6140971 | 0.81 | TP53 (0.59) | HSD17B10KMT2AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042408-A1 | METHODS OF TREATING CANCER | SCHRÖDINGER, INC. (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |