Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | SYK | P43405 | 6/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123142 | 1.00 | PTK6 (0.39) | PTK6DHODHTTKPDE4BPDE4D | |
| Hydrochloric Acid SCHEMBL30386239 | 0.99 | PTK6 (0.39) | PTK6DHODHTTKPDE4BPDE4D | |
| Hydrochloric Acid SCHEMBL22124453 | 0.99 | PTK6 (0.39) | PTK6DHODHTTKPDE4BPDE4D | |
| SCHEMBL30385532 | 0.97 | PTK6 (0.37) | PTK6DHODHTTKPDE4BPDE4D | |
| SCHEMBL22123373 | 0.93 | PTK6 (0.39) | PTK6TTKPDE4BPDE4DSYK | |
| SCHEMBL30168207 | 0.93 | PTK6 (0.39) | PTK6TTKPDE4BPDE4DSYK | |
| SCHEMBL22123585 | 0.93 | PTK6 (0.38) | PTK6DHODHTTKPDE4BPDE4D | |
| SCHEMBL24940106 | 0.93 | SYK (0.44) | PTK6TTKPDE4BPDE4DSYK | |
| SCHEMBL22123265 | 0.92 | PTK6 (0.39) | PTK6DHODHTTKPDE4BPDE4D | |
| SCHEMBL24916600 | 0.92 | PTK2 (0.39) | PTK6TTKSYKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |