Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.49 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24077161 | 1.00 | ALOX15 (0.68) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL26733145 | 0.88 | TSHR (0.53) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL24076931 | 0.86 | CYP2C19 (0.60) | ALOX15CYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL25748370 | 0.86 | ALOX15 (0.51) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL24076925 | 0.85 | ALOX15 (0.70) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL24076920 | 0.85 | ALOX15 (0.70) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL25430777 | 0.83 | ALOX15 (0.49) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL30451946 | 0.83 | ALOX15 (0.49) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL26733180 | 0.83 | ALOX15 (0.49) | ALOX15TSHRAKR1B1CMA1CYP1A2 | |
| SCHEMBL29426564 | 0.82 | ALOX15 (0.51) | ALOX15TSHRAKR1B1CMA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |