Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 14/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24077213 | 1.00 | NLRP3 (0.60) | NLRP3AKR1B1GPR139MAPT | |
| SCHEMBL24077227 | 0.94 | NLRP3 (0.55) | NLRP3AKR1B1 | |
| SCHEMBL24076982 | 0.94 | NLRP3 (0.55) | NLRP3AKR1B1 | |
| SCHEMBL24077286 | 0.92 | NLRP3 (0.56) | NLRP3MAPT | |
| SCHEMBL24076990 | 0.88 | NLRP3 (0.58) | NLRP3 | |
| SCHEMBL24077195 | 0.88 | NLRP3 (0.53) | NLRP3AKR1B1 | |
| SCHEMBL24077353 | 0.87 | NLRP3 (0.63) | NLRP3AKR1B1GPR139MAPT | |
| SCHEMBL24076985 | 0.87 | NLRP3 (0.60) | NLRP3 | |
| SCHEMBL29348126 | 0.86 | NLRP3 (0.44) | NLRP3AKR1B1GPR139MAPT | |
| SCHEMBL24077346 | 0.86 | NLRP3 (0.60) | NLRP3AKR1B1GPR139MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |